Diversity of Secondary Metabolites from Marine Bacillus Species: Chemistry and Biological Activity

Marine Drugs

Muhammad Abdul Mojid Mondol²  Hee Jae Shin¹ 

[1] Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science & Technology, Ansan, P.O. Box 29, Seoul 425-600, Korea;School of Science and Technology, Bangladesh Open University, Board Bazar, Gazipur 1705, Bangladesh; E-Mail:

关键词: bioactive compounds;    macrolactins;    detoxification;    biosynthesis;    carotenoids;    biopesticides;   

DOI  :  10.3390/md11082846

来源: mdpi

【 摘 要 】

Marine Bacillus species produce versatile secondary metabolites including lipopeptides, polypeptides, macrolactones, fatty acids, polyketides, and isocoumarins. These structurally diverse compounds exhibit a wide range of biological activities, such as antimicrobial, anticancer, and antialgal activities. Some marine Bacillus strains can detoxify heavy metals through reduction processes and have the ability to produce carotenoids. The present article reviews the chemistry and biological activities of secondary metabolites from marine isolates. Side by side, the potential for application of these novel natural products from marine Bacillus strains as drugs, pesticides, carotenoids, and tools for the bioremediation of heavy metal toxicity are also discussed.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.