Preventive or Potential Therapeutic Value of Nutraceuticals against Ionizing Radiation-Induced Oxidative Stress in Exposed Subjects and Frequent Fliers

International Journal of Molecular Sciences

Maria Teresa Giardi²  Eleftherios Touloupakis¹  Delfina Bertolotto³ 

[1]Biosensor, Via Olmetti 44 Formello, Rome 00060, Italy

[2] E-Mail:

[3]IC-CNR Area della ricerca di Roma, Monterotondo scalo 00015, Italy

[4]Agenzia Spaziale Italiana (ASI), Viale Liegi 26, Rome 00198, Italy

[5] E-Mails:

关键词: ionizing radiation;    low doses;    oxidation stress;    ageing;    cardiovascular disease;    cancer;    retina degeneration;    antioxidants;    radio-protection;   

DOI  :  10.3390/ijms140817168

来源: mdpi

【 摘 要 】

Humans are constantly exposed to ionizing radiation deriving from outer space sources or activities related to medical care. Absorption of ionizing radiation doses over a prolonged period of time can result in oxidative damage and cellular dysfunction inducing several diseases, especially in ageing subjects. In this report, we analyze the effects of ionizing radiation, particularly at low doses, in relation to a variety of human pathologies, including cancer, and cardiovascular and retinal diseases. We discuss scientific data in support of protection strategies by safe antioxidant formulations that can provide preventive or potential therapeutic value in response to long-term diseases that may develop following exposure.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland