The Characterisation of Pluripotent and Multipotent Stem Cells Using Fourier Transform Infrared Microspectroscopy

International Journal of Molecular Sciences

Julie Cao³  Elizabeth S. Ng³  Donald McNaughton²  Edouard G. Stanley³  Andrew G. Elefanty³  Mark J. Tobin¹ 

[1] Australian Synchrotron, 800 Blackburn Road, Clayton, Victoria 3168, Australia; E-Mail:;Centre for Biospectroscopy and the School of Chemistry, Monash University, Clayton, Victoria 3800, Australia; E-Mail:;Department of Anatomy and Developmental Biology, Faculty of Medicine, Nursing and Health Sciences, Monash University, Wellington Road, Clayton, Victoria 3800, Australia; E-Mails:

关键词: Fourier transform infrared microspectroscopy;    pluripotent stem cells;    multipotent stem cells;    regenerative medicine;   

DOI  :  10.3390/ijms140917453

来源: mdpi

【 摘 要 】

Fourier transform infrared (FTIR) microspectroscopy shows potential as a benign, objective and rapid tool to screen pluripotent and multipotent stem cells for clinical use. It offers a new experimental approach that provides a holistic measurement of macromolecular composition such that a signature representing the internal cellular phenotype is obtained. The use of this technique therefore contributes information that is complementary to that acquired by conventional genetic and immunohistochemical methods.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland