Analysis of EEG via Multivariate Empirical Mode Decomposition for Depth of Anesthesia Based on Sample Entropy

Entropy

Qin Wei³  Quan Liu²  Shou-Zhen Fan⁵  Cheng-Wei Lu¹  Tzu-Yu Lin¹  Maysam F. Abbod⁴ 

[1] Department of Anesthesiology, Far Eastern Memorial Hospital, Ban-Chiao 220, Taiwan; E-Mails:;School of Information Engineering, Wuhan University of Technology, Wuhan 430070, China; E-Mail:;School of Mechanical and Electronic Engineering, Wuhan University of Technology, Wuhan 430070, China; E-Mail:;School of Engineering and Design, Brunel University, London UB8 3PH, UK; E-Mail:;Department of Anesthesiology, College of Medicine, National Taiwan University, Taipei 100, Taiwan; E-Mail:

关键词: electroencephalograph;    sample entropy;    multivariate empirical mode decomposition;    depth of anesthesia;   

DOI  :  10.3390/e15093458

来源: mdpi

【 摘 要 】

In monitoring the depth of anesthesia (DOA), the electroencephalography (EEG) signals of patients have been utilized during surgeries to diagnose their level of consciousness. Different entropy methods were applied to analyze the EEG signal and measure its complexity, such as spectral entropy, approximate entropy (ApEn) and sample entropy (SampEn). However, as a weak physiological signal, EEG is easily subject to interference from external sources such as the electric power, electric knives and other electrophysiological signal sources, which lead to a reduction in the accuracy of DOA determination. In this study, we adopt the multivariate empirical mode decomposition (MEMD) to decompose and reconstruct the EEG recorded from clinical surgeries according to its best performance among the empirical mode decomposition (EMD), the ensemble EMD (EEMD), and the complementary EEMD (CEEMD) and the MEMD. Moreover, according to the comparison between SampEn and ApEn in measuring DOA, the SampEn is a practical and efficient method to monitor the DOA during surgeries at real time.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.