International Journal of Molecular Sciences | |
The DNA-Damage Response to γ-Radiation Is Affected by miR-27a in A549 Cells | |
Andrea Di Francesco1  Cristiano De Pittà1  Francesca Moret1  Vito Barbieri2  Lucia Celotti1  | |
[1] Department of Biology, University of Padova, via U. Bassi 58/B, Padova 35131, Italy; E-Mails:;Department of Surgery, Oncology and Gastroenterology, University of Padova via Gattamelata 64, Padova 35128, Italy; E-Mail: | |
关键词:
γ-radiation;
DNA Damage Response;
miR-27a;
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DOI : 10.3390/ijms140917881 | |
来源: mdpi | |
【 摘 要 】
Perturbations during the cell DNA-Damage Response (DDR) can originate from alteration in the functionality of the microRNA-mediated gene regulation, being microRNAs (miRNAs), small non-coding RNAs that act as post-transcriptional regulators of gene expression. The oncogenic miR-27a is over-expressed in several tumors and, in the present study, we investigated its interaction with
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
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