Oxetane Synthesis through the Paternò-Büchi Reaction

Molecules

Maurizio D𠆚uria¹ 

关键词: photochemistry;    (2+2)-cycloaddition;    oxetanes;    organic synthesis;   

DOI  :  10.3390/molecules180911384

来源: mdpi

【 摘 要 】

The Paternò-Büchi reaction is a photochemical reaction between a carbonyl compound and an alkene to give the corresponding oxetane. In this review the mechanism of the reaction is discussed. On this basis the described use in the reaction with electron rich alkenes (enolethers, enol esters, enol silyl ethers, enanines, heterocyclic compounds has been reported. The stereochemical behavior of the reaction is particularly stressed. We pointed out the reported applications of this reaction to the synthesis of naturally occuring compounds.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.