A New Tetrahydrofuran Lignan Diglycoside from Viola tianshanica Maxim

Molecules

Yan Qin¹  Chengle Yin¹ 

[1] Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 201203, China

关键词: Viola tianshanica;    lignan;    tianshanoside A;    cytotoxicity;   

DOI  :  10.3390/molecules181113636

来源: mdpi

【 摘 要 】

A new lignan glycoside, tianshanoside A (1), together with a known phenylpropanoid glycoside, syringin (2) and two known lignan glycosides, picraquassioside C (3), and aketrilignoside B (4), were isolated from the whole plant of Viola tianshanica Maxim. The structure of the new compound was elucidated by extensive NMR (¹H, ¹³C, COSY, HSQC, HMBC and ROESY) and high resolution mass spectrometry analysis. The three lignans 1, 3, and 4 did not exhibit significant cytotoxicity against human gastric cancer Ags cells or HepG2 liver cancer cells. This is the first report of the isolation of a lignan skeleton from the genus Viola L.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.