Polymers | |
Release of Potassium Ion and Calcium Ion from Phosphorylcholine Group Bearing Hydrogels | |
Hanna R. Aucoin2  A. Nolan Wilson2  Ann M. Wilson1  Kazuhiko Ishihara3  | |
[1] Department of Chemistry, University of the West Indies, St. Augustine, Trinidad and Tobago; E-Mail:;Center for Bioelectronics, Biosensors and Biochips (C3B), Clemson University Advanced Materials Center, 100 Technology Drive, Anderson, SC 29625, USA; E-Mails:;Department of Materials Engineering and Department of Bioengineering, School of Engineering, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-8656, Japan; E-Mail: | |
关键词: calcium ion; potassium ion; diffusion; 2-methacryloyloxyethyl phosphorylcholine; poly(2-hydroxyethyl methacrylate); hydrogel matrix; Zwitterionic; HEMA; | |
DOI : 10.3390/polym5041241 | |
来源: mdpi | |
【 摘 要 】
In an attempt to recreate the microenvironment necessary for directed hematopoietic stem cell differentiation, control over the amount of ions available to the cells is necessary. The release of potassium ion and calcium ion via the control of cross-linking density of a poly(2-hydroxyethyl methacrylate) (pHEMA)-based hydrogel containing 1 mol % 2-methacryloyloxyethyl phosphorylcholine (MPC) and 5 mol % oligo(ethylene glycol) (400) monomethacrylate [OEG(400)MA] was investigated. Tetra(ethylene glycol) diacrylate (TEGDA), the cross-linker, was varied over the range of 1–12 mol %. Hydrogel discs (
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190031827ZK.pdf | 581KB | download |