Vitamin K Status in Chronic Kidney Disease

Nutrients

Kristin M. McCabe¹  Michael A. Adams¹ 

[1]Department of Biomedical and Molecular Sciences, Queen’s University, Kingston, ON K7L 3V6, Canada

[2] E-Mails:

关键词: vitamin K;    chronic kidney disease;    renal insufficiency;    vitamin K-dependent proteins;   

DOI  :  10.3390/nu5114390

来源: mdpi

【 摘 要 】

The purpose of this review is to summarize the research to date on vitamin K status in chronic kidney disease (CKD). This review includes a summary of the data available on vitamin K status in patients across the spectrum of CKD as well as the link between vitamin K deficiency in CKD and bone dynamics, including mineralization and demineralization, as well as ectopic mineralization. It also describes two current clinical trials that are underway evaluating vitamin K treatment in CKD patients. These data may inform future clinical practice in this population.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.