Molecules | |
Bio-Activity and Dereplication-Based Discovery of Ophiobolins and Other Fungal Secondary Metabolites Targeting Leukemia Cells | |
Tanja Thorskov Bladt2  Claudia Dürr3  Peter Boldsen Knudsen2  Sara Kildgaard2  Jens Christian Frisvad2  Charlotte Held Gotfredsen1  Martina Seiffert3  | |
[1]Department of Chemistry, Technical University of Denmark, Kemitorvet, Building 201, Kgs. Lyngby DK-2800, Denmark | |
[2] E-Mail: | |
[3]Department of Systems Biology, Technical University of Denmark, Søltofts Plads, Building 221, Kgs. Lyngby DK-2800, Denmark | |
[4] E-Mails: | |
[5]German Cancer Research Center, Molecular Genetics, Im Neuenheimer Feld 280, Heidelberg D-69120, Germany | |
[6] E-Mail: | |
关键词: natural products; ophiobolin U; dereplication; explorative solid phase extraction (E-SPE); filamentous fungi; cytotoxic; cancer; leukemia; | |
DOI : 10.3390/molecules181214629 | |
来源: mdpi | |
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【 摘 要 】
The purpose of this study was to identify and characterize fungal natural products (NPs) with
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190031213ZK.pdf | 746KB | ![]() |