Pestalafuranones F–J, Five New Furanone Analogues from the Endophytic Fungus Nigrospora sp. BM-2

Molecules

Hongqi Zhang²  Zhangshuang Deng¹  Zhiyong Guo²  Xuan Tu²  Junzhi Wang² 

[1] id="af1-molecules-19-00819">Hubei Key Laboratory of Natural Products Research and Development, College of Chemistry and Life Science, China Three Gorges University, Yichang 443002, Chi

关键词: pestalafuranones F–J;    endophytic fungus;    Nigrospora sp.;    cytotoxic activity;   

DOI  :  10.3390/molecules19010819

来源: mdpi

【 摘 要 】

Five new 2(5H)-furanone-type derivatives, pestalafuranones F–J (compounds 3–7), together with two known compounds, pestalafuranones A (1) and B (2), were isolated from the ethyl acetate extract from the fermentation broth of the endophytic fungus Nigrospora sp. BM-2 in a hypersaline medium. The structures of these metabolites were elucidated by EIMS, HREIMS and NMR spectroscopic data. Compounds 1–7 exhibited no cytotoxic activities against the MDA-MB-231 and Caski cancer cell lines.

【 授权许可】

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