Toxins | |
Food Poisonings by Ingestion of Cyprinid Fish | |
Manabu Asakawa1  | |
[1] Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, Hiroshima 739-8528, Japan | |
关键词: cyprinid fish; gallbladder; bile alcohol; Thin layer chromatography; acute renal failure; acute dysfunction of liver; FAB mass spectrometry; IR spectrometry; NMR spectrometry; | |
DOI : 10.3390/toxins6020539 | |
来源: mdpi | |
【 摘 要 】
Raw or dried gallbladders of cyprinid fish have long been ingested as a traditional medicine in the Asian countries, particularly in China, for ameliorating visual acuity, rheumatism, and general health; however, sporadic poisoning incidences have occurred after their ingestion. The poisoning causes complex symptoms in patients, including acute renal failure, liver dysfunction, paralysis, and convulsions of limbs. The causative substance for the poisoning was isolated, and its basic properties were examined. The purified toxin revealed a minimum lethal dose of 2.6 mg/20 g in mouse, when injected intraperitoneally
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190029490ZK.pdf | 2312KB | download |