期刊论文详细信息
Molecules | |
Pauson-Khand Reaction of Internal Dissymmetric Trifluoromethyl Alkynes. Influence of the Alkene on the Regioselectivity | |
Nuria Aiguabella2  Elsa M. Arce2  Carlos del Pozo1  Xavier Verdaguer2  | |
[1] Department de Química Orgánica, Universidad de Valencia, E-46100 Burjassot, Spain; E-Mail:;Institute for Research in Biomedicine (IRB Barcelona), Baldiri i Reixac, 10. 08028 Barcelona, Spain; E-Mails: | |
关键词: Pauson-Khand reaction; cycloadditions; regioselectivity; cyclopentenones; trifluoromethylalkynes; | |
DOI : 10.3390/molecules19021763 | |
来源: mdpi | |
【 摘 要 】
The scope of the Pauson-Khand reaction (PKR) of internal trifluoromethyl alkynes, previously described with norbornadiene, is expanded to norbornene and ethylene. A thorough structural analysis of the resulting PK adducts has been carried out to unveil that α-trifluoromethylcyclopentenones are preferred in all cases, independently of the electronic properties of the alkyne. The regioselectivity observed with norbornadiene and ethylene is higher than in the case of norbornene.
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190029270ZK.pdf | 237KB | download |