Toxins | |
Botulinum Neurotoxin A Complex Recognizes Host Carbohydrates through Its Hemagglutinin Component | |
Guorui Yao1  Kwangkook Lee1  Shenyan Gu1  Kwok-Ho Lam1  | |
[1] Department of Physiology and Biophysics, University of California, Irvine, CA 92697, USA; | |
关键词: Botulinum neurotoxins (BoNTs); progenitor toxin complex (PTC); hemagglutinin (HA); carbohydrate receptor; glycan array; | |
DOI : 10.3390/toxins6020624 | |
来源: mdpi | |
【 摘 要 】
Botulinum neurotoxins (BoNTs) are potent bacterial toxins. The high oral toxicity of BoNTs is largely attributed to the progenitor toxin complex (PTC), which is assembled from BoNT and nontoxic neurotoxin-associated proteins (NAPs) that are produced together with BoNT in bacteria. Here, we performed
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190029115ZK.pdf | 1775KB | download |