Notes on the Epidemiology of Multiple Sclerosis, with Special Reference to Dietary Habits

International Journal of Molecular Sciences

关键词: multiple sclerosis;    epidemiology;    diet;    meat;    nitrophenols;   

DOI  :  10.3390/ijms15033533

来源: mdpi

【 摘 要 】

A hypothesis, based primarily on the occurrence of multiple sclerosis (MS) in the Faroe Islands and supported by numerous analytical epidemiological studies, is described. It proposes that MS is caused by the interaction of a virus disease with intestinal pathology, e.g., infectious mononucleosis, and application of smoked and nitrate/nitrite-cured meat products in the diet during circumscribed time intervals. The biological mechanisms might involve a break of tolerance by an alteration of self within the central nervous system, by nitrophenylated compounds conjugated to animal tissue, in particular to proteins occurring in the central nervous system. Further research is needed.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland