International Journal of Molecular Sciences | |
A Preliminary X-ray Study of Murine Tnfaip8/Oxi-α | |
Daeun Lee2  Mi-Sun Kim2  Jimin Park2  Gil-Ja Jhon1  Jin H. Son2  | |
[1] Department of Chemistry and Nano Science, Global Top5 Research Program, Ewha Womans University, Seoul 120-750, Korea; E-Mail:;College of Pharmacy and Graduate School of Pharmaceutical Sciences, Global Top5 Research Program, Ewha Womans University, Seoul 120-750, Korea; E-Mails: | |
关键词: Parkinson’s disease; Oxi-α; oxidative stress; C165S mutant; X-ray crystallography; | |
DOI : 10.3390/ijms15034523 | |
来源: mdpi | |
【 摘 要 】
Tnfaip8/oxidative stress regulated gene-α (Oxi-α) is a novel protein expressed specifically in brain dopaminergic neurons and its over-expression has been reported to protect dopaminergic cells against OS-induced cell death. In this study, murine C165S mutant Tnfaip8/Oxi-α has been crystallized and X-ray data have been collected to 1.8 Å using synchrotron radiation. The crystal belonged to the primitive orthorhombic space group P21212, with unit-cell parameters
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland
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