Super-Resolution Microscopy: A Virus’ Eye View of the Cell

Viruses

关键词: microscopy;    super-resolution;    PALM;    STORM;    dSTORM;    tetraspanin;    virus assembly;    virus entry;   

DOI  :  10.3390/v6031365

来源: mdpi

【 摘 要 】

It is difficult to observe the molecular choreography between viruses and host cell components, as they exist on a spatial scale beyond the reach of conventional microscopy. However, novel super-resolution microscopy techniques have cast aside technical limitations to reveal a nanoscale view of virus replication and cell biology. This article provides an introduction to super-resolution imaging; in particular, localisation microscopy, and explores the application of such technologies to the study of viruses and tetraspanins, the topic of this special issue.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.