New Terpenes from the Egyptian Soft Coral Sarcophyton ehrenbergi

Marine Drugs

Ahmed Elkhateeb³  Ahmed A. El-Beih⁵  Amira M. Gamal-Eldeen⁶  Montaser A. Alhammady⁴  Shinji Ohta¹  Paul W. Paré² 

[1] Graduate School of Biosphere Science, Hiroshima University, 1-7-1 Kagamiyama, Higashi-Hiroshima 739-852, Japan; E-Mail:;Department of Chemistry & Biochemistry, Texas Tech University, Lubbock, TX 79409, USA; E-Mail:;Phytochemistry and Plant Systematic Department, National Research Centre, El-Tahrir St., Dokki, Giza 12311, Egypt; E-Mail:;National Institute of Oceanography and Fisheries, Red Sea Branch, Hurghada 84511, Egypt; E-Mail:;Department of Chemistry of Natural & Microbial Products, Center of Excellence Advanced Sciences, National Research Centre, El-Tahrir Street, Dokki, Giza 12311, Egypt; E-Mail:;Cancer Biology Lab, Center of Excellence for Advanced Sciences & Biochemistry Department, National Research Center, Dokki, Cairo 12311, Egypt; E-Mail:

关键词: Sarcophyton ehrenbergi;    soft coral;    terpenes;    cembranoids;    sesquiterpenes;    cytotoxic activity;   

DOI  :  10.3390/md12041977

来源: mdpi

【 摘 要 】

Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1–3 as well as the previously reported marine cembranoid diterpene sarcophine (4). Structures were elucidated by comprehensive NMR and HRMS experimentation. Isolated compounds were in vitro assayed for cytotoxic activity against human hepatocarcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines.

【 授权许可】

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.