International Journal of Molecular Sciences | |
MicroRNA-103 Promotes Colorectal Cancer by Targeting Tumor Suppressor DICER and PTEN | |
Li Geng2  Bing Sun3  Bo Gao2  Zheng Wang2  Cheng Quan2  Feng Wei1  | |
[1] Department of Hepatobiliary and Pancreas Surgery, the First Hospital, Jilin University, Changchun 130021, Jilin, China;Department of General Surgery, the Second Hospital of Jilin University, Changchun 130041, Jilin, China; E-Mails:;Department of Neurology, Changchun Central Hospital, Changchun 130041, Jilin, China; E-Mail: | |
关键词:
miR-103;
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DOI : 10.3390/ijms15058458 | |
来源: mdpi | |
【 摘 要 】
MicroRNAs (miRNAs) are a class of small, noncoding RNAs that act as key regulators in various physiological and pathological processes. However, the regulatory mechanisms for miRNAs in colorectal cancer remain largely unknown. Here, we found that miR-103 is up-regulated in colorectal cancer and its overexpression is closely associated with tumor proliferation and migration. In addition, repressing the expression of miR-103 apparently inhibits colorectal cancer cell proliferation and migration
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
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