International Journal of Molecular Sciences | |
Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition | |
Yongqiang Liang2  Haoyan Li3  Jiang Xu1  Xin Li3  Mengchun Qi3  | |
[1] Department of stomatology, Tongchuan City People’s Hospital, Tongchuan 727000, China; E-Mail:;Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, China; E-Mail:;College of Stomatology, Hebei United University, Tangshan 063000, China; E-Mails: | |
关键词: strontium; brushite; coating; implant; osteoblast; biomedical materials; | |
DOI : 10.3390/ijms15069952 | |
来源: mdpi | |
【 摘 要 】
Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on titanium by electrochemical deposition. The phase composition of the coating was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy, and the cytocompatibility and bioactivity of the strontium-doped brushite coatings were evaluated using cultured osteoblasts. Osteoblast proliferation was enhanced by the addition of strontium, suggesting a possible mechanism by which strontium incorporation in brushite coatings increased bone formation surrounding the implants. Cell growth was also strongly influenced by the composition of the deposited coatings, with a 10% Sr-doped brushite coating inducing the greatest amount of bone formation among the tested materials.
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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