Morphology, Composition, and Bioactivity of Strontium-Doped Brushite Coatings Deposited on Titanium Implants via Electrochemical Deposition

International Journal of Molecular Sciences

Yongqiang Liang²  Haoyan Li³  Jiang Xu¹  Xin Li³  Mengchun Qi³ 

[1] Department of stomatology, Tongchuan City People’s Hospital, Tongchuan 727000, China; E-Mail:;Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, China; E-Mail:;College of Stomatology, Hebei United University, Tangshan 063000, China; E-Mails:

关键词: strontium;    brushite;    coating;    implant;    osteoblast;    biomedical materials;   

DOI  :  10.3390/ijms15069952

来源: mdpi

【 摘 要 】

Surface modification techniques have been applied to generate titanium implant surfaces that promote osseointegration for use in dental applications. In this study, strontium-doped brushite coatings were deposited on titanium by electrochemical deposition. The phase composition of the coating was investigated by energy dispersive X-ray spectroscopy and X-ray diffraction. The surface morphologies of the coatings were studied through scanning electron microscopy, and the cytocompatibility and bioactivity of the strontium-doped brushite coatings were evaluated using cultured osteoblasts. Osteoblast proliferation was enhanced by the addition of strontium, suggesting a possible mechanism by which strontium incorporation in brushite coatings increased bone formation surrounding the implants. Cell growth was also strongly influenced by the composition of the deposited coatings, with a 10% Sr-doped brushite coating inducing the greatest amount of bone formation among the tested materials.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.