Host Pathogen Relations: Exploring Animal Models for Fungal Pathogens

Pathogens

Catherine G. Harwood¹ 

[1] Biology and Biotechnology Department, Worcester Polytechnic University, Worcester, MA 01605, USA; E-Mail

关键词: fungal pathogens;    Candida;    Cryptococcus;    Histoplasma;    Aspergillus;    model host systems;   

DOI  :  10.3390/pathogens3030549

来源: mdpi

【 摘 要 】

Pathogenic fungi cause superficial infections but pose a significant public health risk when infections spread to deeper tissues, such as the lung. Within the last three decades, fungi have been identified as the leading cause of nosocomial infections making them the focus of research. This review outlines the model systems such as the mouse, zebrafish larvae, flies, and nematodes, as well as ex vivo and in vitro systems available to study common fungal pathogens.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.