Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover

Cosmetics

Mina Musashi²  Ariella Coler-Reilly¹  Teruaki Nagasawa²  Yoshiki Kubota²  Satomi Kato¹ 

[1] Institute of Medical Science, School of Medicine, St. Marianna University, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8512, Japan; E-Mails:;NANOEGG^® Research Laboratories, Inc., 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8512, Japan; E-Mails:

关键词: liquid crystal;    skin turnover;    intercellular lipids;    stratum corneum;    age spots;    skin care;   

DOI  :  10.3390/cosmetics1030202

来源: mdpi

【 摘 要 】

Studies have shown that liquid crystals structurally resembling the intercellular lipids in the stratum corneum can beneficially affect the skin when applied topically by stimulating the skin’s natural regenerative functions and accelerating epidermal turnover. In the present study, the effects of applying low concentrations of a liquid crystal gel of our own creation were evaluated using epidermal thickening in mouse skin as an assay for effective stimulation of epidermal turnover. A liquid crystal gel was also applied topically to human facial skin, and analysis was conducted using before-and-after photographs of age spots, measurements of L* values that reflect degree of skin pigmentation, single-layer samples of the stratum corneum obtained via tape-stripping, and measurements of trans-epidermal water loss that reflect the status of the skin’s barrier function. The results suggested that cost-effective creams containing as low as 5% liquid crystal gel might be effective and safely sold as skin care products targeting age spots and other problems relating to uneven skin pigmentation.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.