The Constituents of Roots and Stems of Illigera luzonensis and Their Anti-Platelet Aggregation Effects

International Journal of Molecular Sciences

Chieh-Hung Huang⁴  Yu-Yi Chan³  Ping-Chung Kuo¹  Yu-Fon Chen²  Ren-Jie Chang⁴  Ih-Sheng Chen⁵  Shwu-Jen Wu⁶ 

[1] Department of Biotechnology, National Formosa University, Yunlin 63201, Taiwan; E-Mail:;Department of Life Sciences, National Cheng Kung University, Tainan 70101, Taiwan; E-Mail:;Department of Biotechnology, Southern Taiwan University of Technology, Tainan 71005, Taiwan; E-Mail:;Department of Chemistry, National Cheng Kung University, Tainan 70101, Taiwan; E-Mails:;Department of Pharmacy, Kaohsiung Medical University, Kaohsiung 80708, Taiwan; E-Mail:;Department of Medical Laboratory Science and Biotechnology, Chung Hwa University of Medical Technology, Tainan 71703, Taiwan

关键词: Illigera luzonensis;    aporphine;    alkaloid;    benzenoid;    anti-platelet aggregation effect;   

DOI  :  10.3390/ijms150813424

来源: mdpi

【 摘 要 】

Phytochemical investigation of the roots and stems of Illigera luzonensis afforded two new aporphine alkaloids (1) and (2), one new bisdehydroaporphine alkaloid (3), and one new benzenoid (4), along with 28 known structures. The structures of new compounds were elucidated by spectral and MS analysis. Among the isolated compounds, (1) and (4–13) were subjected into the examination for their inhibitory effects on the aggregation of washed rabbit platelets.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.