International Journal of Molecular Sciences | |
Epigenetic Determinants of |
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Sabine U. Vorrink1  Danielle R. Hudachek2  | |
[1] Interdisciplinary Graduate Program in Human Toxicology, the University of Iowa, Iowa City, IA 52242, USA; E-Mail:;Department of Radiation Oncology, the University of Iowa, Iowa City, IA 52242, USA | |
关键词: aryl hydrocarbon receptor; chromatin accessibility; DNA methylation; epigenetic regulation; polychlorinated biphenyls; | |
DOI : 10.3390/ijms150813916 | |
来源: mdpi | |
【 摘 要 】
Many enzymes involved in xenobiotic metabolism, including cytochrome P450 (CYP) 1A1, are regulated by the aryl hydrocarbon receptor (AhR). 3,3',4,4',5-Pentachlorobiphenyl (PCB 126) is a potent ligand for AhR and can thus induce the expression of
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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