Nutrients | |
Piperine Inhibits the Activities of Platelet Cytosolic Phospholipase A2 and Thromboxane A2 Synthase without Affecting Cyclooxygenase-1 Activity: Different Mechanisms of Action Are Involved in the Inhibition of Platelet Aggregation and Macrophage Inflammatory Response | |
Dong Ju Son3  Satoshi Akiba2  Jin Tae Hong4  Yeo Pyo Yun4  Seock Yeon Hwang1  Young Hyun Park5  | |
[1] Department of Biomedical Laboratory Science, College of Natural Science, Daejeon 300-716, Korea; E-Mail:;Department of Pathological Biochemistry, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan; E-Mail:;School of Applied Biosciences, Kyungpook National University, Daegu 702-701, Korea; E-Mail:;College of Pharmacy and Center for Innovative Cancer Therapeutics, Chungbuk National University, Cheongju 361-763, Korea; E-Mails:;Department of Food Science and Nutrition, College of Natural Sciences, Soonchunhayng University, Asan 336-745, Korea | |
关键词: pepper; piperine; platelet aggregation; arachidonic acid; cyclooxygenase; phospholipase A2; thromboxane A2 synthase; prostaglandins; | |
DOI : 10.3390/nu6083336 | |
来源: mdpi | |
【 摘 要 】
PURPOSE: Piperine, a major alkaloid of black pepper (
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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