Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles

Molecules

Tauqir A. Nizami¹ 

[1] Department of Chemistry, Tsinghua University, Beijing 100084, China; E-Mail

关键词: 1;    3-butadiynes;    cycloaddition;    cabocycles;    heterocycles;   

DOI  :  10.3390/molecules190913788

来源: mdpi

【 摘 要 】

Cycloaddition reactions of alkynes are elegant, atom-efficient transformations for the synthesis of carbo- and heterocycles, mostly aromatic, involving the construction of challenging skeletons of complex molecules. Therefore significant efforts have recently been devoted to the development of novel methodologies, efficient strategies and different catalytic systems to broaden the scope of these reactions. We summarize in this review the recent advances in the cycloaddition reactions of 1,3-butadiynes to provide facile and reliable approaches to various functionalized carbo- and heterocycles.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.