Photochemical Aryl Radical Cyclizations to Give (E)-3-Ylideneoxindoles

Molecules

Michael Gurry¹  Ingrid Allart-Simon³  Patrick McArdle¹  Stéphane Gérard³  Janos Sapi³  Fawaz Aldabbagh¹  John C. Walton² 

[1] School of Chemistry, National University of Ireland Galway, University Road, Galway, Ireland;id="af1-molecules-19-15891">1School of Chemistry, National University of Ireland Galway, University Road, Galway, Irela;Institut de Chimie Moléculaire de Reims, UMR CNRS 7312, Université de Reims-Champagne-Ardenne, Faculté de Pharmacie, 51 rue Cognacq-Jay, F-51096 Reims Cedex, France

关键词: cyclization;    heterocycle;    oxindole;    UV-light;   

DOI  :  10.3390/molecules191015891

来源: mdpi

【 摘 要 】

(E)-3-Ylideneoxindoles are prepared in methanol in reasonable to good yields, as adducts of photochemical 5-exo-trig of aryl radicals, in contrast to previously reported analogous radical cyclizations initiated by tris(trimethylsilyl)silane and azo-initiators that gave reduced oxindole adducts.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.