Sensors | |
Single-Molecule Study of Proteins by Biological Nanopore Sensors | |
Dongmei Wu1  Sheng Bi2  Liyu Zhang1  | |
[1] College of Pharmacy, Jiamusi University, Jiamusi 154007, China; E-Mail:;The Affiliated First Hospital of Jiamusi University, Jiamusi 154007, China; E-Mail: | |
关键词: α-hemolysin; protein conformation; protein-ligand interactions; new nanopores; | |
DOI : 10.3390/s141018211 | |
来源: mdpi | |
【 摘 要 】
Nanopore technology has been developed for detecting properties of proteins through monitoring of ionic current modulations as protein passes via a nanosize pore. As a real-time, sensitive, selective and stable technology, biological nanopores are of widespread concern. Here, we introduce the background of nanopore researches in the area of α-hemolysin (α-HL) nanopores in protein conformation detections and protein–ligand interactions. Moreover, several original biological nanopores are also introduced with various features and functions.
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190021190ZK.pdf | 2639KB | download |