Bioactivity and Chemical Synthesis of Caffeic Acid Phenethyl Ester and Its Derivatives

Molecules

Pengxuan Zhang¹  Yuping Tang¹  Nian-Guang Li¹  Yue Zhu¹  Jin-Ao Duan¹ 

[1]Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, Nanjing University of Chinese Medicine, Nanjing 210023, China

关键词: caffeic acid phenethyl ester;    chemical structure;    biological;    synthetic method;    structural modification;   

DOI  :  10.3390/molecules191016458

来源: mdpi

【 摘 要 】

Caffeic acid phenethyl ester (CAPE), as one of the main active ingredients of the natural product propolis, shows the unique biological activities such as anti-tumor, anti-oxidation, anti-inflammatory, immune regulation, and so on. These have attracted the attention of many researchers to explore the compound with potent biological activities. This review aims to summarize its bioactivities, synthetic methods and derivatives, which will be helpful for further study and development of CAPE and its derivatives.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.