A Comprehensive Review of the Structure Elucidation and Biological Activity of Triterpenoids from Ganoderma spp.

Molecules

Qing Xia²  Huazheng Zhang¹  Xuefei Sun²  Haijuan Zhao²  Lingfang Wu²  Dan Zhu²  Guanghui Yang²  Yanyan Shao²  Xiaoxue Zhang²  Xin Mao²  Lanzhen Zhang²  Gaimei She² 

[1] School of Basic Medical Sciences, Beijing University of Chinese Medicine, Beijing 100029, China; E-Mail:;School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China; E-Mails:

关键词: Ganoderma;    triterpenes;    chemical structure;    ¹³C-NMR data;    bioactivity;   

DOI  :  10.3390/molecules191117478

来源: mdpi

【 摘 要 】

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum, a traditional Chinese medicine, popularly used for complementary cancer therapy. GTs are lanostane-tetracyclic triterpenes. They have been reported to possess anti-tumor, anti-inflammation, antioxidant, antimicrobial and blood fat reducing effects. To date, 316 GTs have been found and their similar chemical structures have proved difficult to elucidate. This paper compiles 316 naturally occurring triterpenes from Ganoderma based on the literature published through January 2013 along with their structures, physiological activities and ¹³C-NMR spectral data.

【 授权许可】

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© 2014 by the authors; licensee MDPI, Basel, Switzerland.