A Systematic Review of Recent Advances in Equine Influenza Vaccination

Vaccines

关键词: equine influenza;    vaccine;    equid;   

DOI  :  10.3390/vaccines2040797

来源: mdpi

【 摘 要 】

Equine influenza (EI) is a major respiratory disease of horses, which is still causing substantial outbreaks worldwide despite several decades of surveillance and prevention. Alongside quarantine procedures, vaccination is widely used to prevent or limit spread of the disease. The panel of EI vaccines commercially available is probably one of the most varied, including whole inactivated virus vaccines, Immuno-Stimulating Complex adjuvanted vaccines (ISCOM and ISCOM-Matrix), a live attenuated equine influenza virus (EIV) vaccine and a recombinant poxvirus-vectored vaccine. Several other strategies of vaccination are also evaluated. This systematic review reports the advances of EI vaccines during the last few years as well as some of the mechanisms behind the inefficient or sub-optimal response of horses to vaccination.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.