Volatile Profiling of Aromatic Traditional Medicinal Plant, Polygonum minus in Different Tissues and Its Biological Activities

Molecules

Rafidah Ahmad¹  Syarul Nataqain Baharum¹  Hamidun Bunawan¹  Minki Lee²  Normah Mohd Noor¹  Emelda Roseleena Rohani¹  Norashikin Ilias¹  Noraziah Mohamad Zin³ 

[1] Metabolomics Research Laboratory, Institute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi 43600, Selangor, Malaysia; E-Mails:;Department of Bio-Environment Chemistry, Chungnam National University, 99 Daehak-Ro, Yuseong-Gu, Daejon 305-764, Korea; E-Mail:;Programme of Biomedical Science, Faculty of Health Sciences, School of Diagnostic and Applied Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia; E-Mail:

关键词: Polygonum minus;    volatile compound;    different tissues;    solid-phase microextractions;    gas chromatography;    biological activities;    essential oil;   

DOI  :  10.3390/molecules191119220

来源: mdpi

【 摘 要 】

The aim of this research was to identify the volatile metabolites produced in different organs (leaves, stem and roots) of Polygonum minus, an important essential oil producing crop in Malaysia. Two methods of extraction have been applied: Solid Phase Microextraction (SPME) and hydrodistillation coupled with Gas Chromatography-Mass Spectrometry (GC-MS). Approximately, 77 metabolites have been identified and aliphatic compounds contribute significantly towards the aroma and flavour of this plant. Two main aliphatic compounds: decanal and dodecanal were found to be the major contributor. Terpenoid metabolites were identified abundantly in leaves but not in the stem and root of this plant. Further studies on antioxidant, total phenolic content, anticholinesterase and antimicrobial activities were determined in the essential oil and five different extracts. The plant showed the highest DPPH radical scavenging activity in polar (ethanol) extract for all the tissues tested. For anti-acetylcholinesterase activity, leaf in aqueous extract and methanol extract showed the best acetylcholinesterase inhibitory activities. However, in microbial activity, the non-polar extracts (n-hexane) showed high antimicrobial activity against Methicillin-resistant Staphylococcus aureus (MRSA) compared to polar extracts. This study could provide the first step in the phytochemical profiles of volatile compounds and explore the additional value of pharmacology properties of this essential oil producing crop Polygonum minus.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.