Molecules | |
Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry | |
Emma-Dune Leriche2  Marie Hubert-Roux2  Carlos Afonso2  Catherine M. Lange2  Martin C. Grossel1  Florian Maire2  Corinne Loutelier-Bourhis2  | |
[1] School of Chemistry, University of Southampton, Highfield, Hants SO17 1BJ Southampton, UK;Normandie Université, COBRA, UMR6014 and FR3038, Université de Rouen; INSA de Rouen; CNRS, IRCOF, 1 rue Tesnière, 76821 Mont-Saint-Aignan Cedex, France | |
关键词: polyamidoamine dendrimers; oligonucleotide duplex; dendriplexes; electrospray mass spectrometry; tandem mass spectrometry; ion mobility spectrometry; | |
DOI : 10.3390/molecules191220731 | |
来源: mdpi | |
【 摘 要 】
Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190018770ZK.pdf | 3141KB | download |