Synthetic Approaches to the Lamellarins—A Comprehensive Review

Marine Drugs

Dennis Imbri²  Johannes Tauber²  Till Opatz¹ 

[1] Institute of Organic Chemistry, Johannes Gutenberg-University Mainz, Duesbergweg 10-14, 55128 Mainz, Germany;

关键词: lamellarins;    pyrroles;    alkaloids;    marine natural products;    total synthesis;   

DOI  :  10.3390/md12126142

来源: mdpi

【 摘 要 】

The present review discusses the known synthetic routes to the lamellarin alkaloids published until 2014. It begins with syntheses of the structurally simpler type-II lamellarins and then focuses on the larger class of the 5,6-saturated and -unsaturated type-I lamellarins. The syntheses are grouped by the strategy employed for the assembly of the central pyrrole ring.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.