International Journal of Molecular Sciences | |
Transmembrane Signal Transduction in Oocyte Maturation and Fertilization: Focusing on |
|
Ken-ichi Sato1  | |
[1] Laboratory of Cell Signaling and Development, Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University, Kamigamo-motoyama, Kita-ku, Kyoto 603-8555, Japan; E-Mail | |
关键词: fertilization; gamete interaction and fusion; membrane microdomains; oocyte maturation; signaling crosstalk; Src; uroplakin III; | |
DOI : 10.3390/ijms16010114 | |
来源: mdpi | |
【 摘 要 】
Fertilization is a cell biological phenomenon of crucial importance for the birth of new life in a variety of multicellular and sexual reproduction species such as algae, animal and plants. Fertilization involves a sequence of events, in which the female gamete “egg” and the male gamete “spermatozoon (sperm)” develop, acquire their functions, meet and fuse with each other, to initiate embryonic and zygotic development. Here, it will be briefly reviewed how oocyte cytoplasmic components are orchestrated to undergo hormone-induced oocyte maturation and sperm-induced activation of development. I then review how sperm-egg membrane interaction/fusion and activation of development in the fertilized egg are accomplished and regulated through egg coat- or egg plasma membrane-associated components, highlighting recent findings and future directions in the studies using
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190018265ZK.pdf | 770KB | download |