Behavioral mechanisms of mammalian sperm guidance

Asian Journal of Andrology

关键词: gene regulation;    Musashi;    Musashi-1;    Musashi-2;    posttranscriptional control;    RNA binding proteins;    spermatogenesis;    splicing;    testis;    translation;    cell fate;    cell stress;    importin;    karyopherin;    nucleocytoplasmic transport;    spermatid;    spermatocyte;    spermatogenesis;    artificial insemination;    biomarker;    fertility;    fertilization;    flow cytometry;    infertility;    nanotechnology;    oocyte activation;    Postacrosomal Sheath WWI Domain Binding Protein;    sperm;    SPTRX3;    thioredoxin;    ubiquitin;    ATP binding cassette transporters;    albumin;    high-density lipoprotein;    lipid rafts;    membrane fluidity;    membrane microdomains;    membrane packing;    oxysterols;    reverse cholesterol transport;    sterol transporters;    egg;    fertilization;    heat shock protein A2;    molecular chaperone;    sperm;    sperm-egg interactions;    dehydrogenases;    oxidases;    peroxiredoxins;    reactive oxygen species;    spermatozoa;    thiols;    thioredoxins;    antigen-presenting cells;    autoimmunity;    dendritic cells;    epididymis;    macrophages;    peripheral tolerance;    sperm maturation;    spermatozoa;    genomics;    male infertility;    proteomics;    sperm chromatin;    sperm epigenetics;    sperm DNA damage;    paternal genome;    offspring;    infertility;    chemotaxis;    rheotaxis;    sperm behavior;    sperm motility;    thermotaxis;   

DOI  :  10.4103/1008-682X.154308

来源: DOAJ

【 摘 要 】

In mammals, sperm guidance in the oviduct appears essential for successful sperm arrival at the oocyte. Hitherto, three different potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using specific stimuli - a temperature gradient, fluid flow, and a chemoattractant gradient, respectively. Here, we review sperm behavioral in these mechanisms and indicate commonalities and differences between them.

【 授权许可】

Unknown