Molecules | |
Synthesis and Anti- |
|
Júlio César L. Menezes1  Luana Beatriz A. Vaz2  Paula Melo de Abreu Vieira2  Kátia da Silva Fonseca2  Cláudia Martins Carneiro2  Jason G. Taylor1  | |
[1] Departamento de Química, ICEB, Universidade Federal de Ouro Preto, Campus Morro do Cruzeiro, CEP, Ouro Preto, MG 35400-000, Brazil; E-Mail:;Laboratório de Imunopatologia, Núcleo de Pesquisas em Ciências Biológicas, ICEB II, Morro do Cruzeiro, Universidade Federal de Ouro Preto, Ouro Preto 35400-000, Brazil; E-Mails: | |
关键词:
diaryldiazepines;
|
|
DOI : 10.3390/molecules20010043 | |
来源: mdpi | |
【 摘 要 】
Chagas disease is a so-called “neglected disease” and endemic to Latin America. Nifurtimox and benznidazole are drugs that have considerable efficacy in the treatment of the acute phase of the disease but cause many significant side effects. Furthermore, in the Chronic Phase its efficiency is reduced and their therapeutic effectiveness is dependent on the type of
【 授权许可】
CC BY
© 2014 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190018253ZK.pdf | 710KB | download |