Flavonoids from Symplocos racemosa

Molecules

Mila Jung³  Janggyoo Choi²  Hee-Sung Chae⁷  Jae Youl Cho⁴  Young-Dong Kim⁵  Khin Myo Htwe⁶  Woo-Shin Lee¹  Young-Won Chin⁷  Jinwoong Kim²  Kee Dong Yoon³ 

[1]Department of Forest Sciences, Seoul National University, Seoul 151-921, Korea

[2] E-Mail:

[3]College of Pharmacy and Research Institute of Pharmaceutical Science, Seoul National University, Seoul 151-742, Korea

[4] E-Mails:

[5]College of Pharmacy, The Catholic University of Korea, Bucheon 420-743, Korea

[6] E-Mail:

[7]Department of Genetic Engineering, Sungkyunkwan University, Suwon 440-746, Korea

[8] E-Mail:

[9]Department of Life Science, Hallym University, Chuncheon 200-702, Korea

[10] E-Mail:

[11]Popa Mountain Park, Forest Department, Kyaukpadaung Township, Mandalay Division, Myanmar

[12] E-Mail:

[13]College of Pharmacy and RFIND-BKplus Team, Dongguk University-Seoul, 32 Dongguk-lo, Ilsan dong-gu, Goyang, Gyeonggi-do 410-820, Korea

[14] E-Mails:

关键词: flavonoids;    sympracemoside;    Symplocos racemosa;   

DOI  :  10.3390/molecules20010358

来源: mdpi

【 摘 要 】

A novel isoflavone glycoside, peseudobatigenin 7-O-[β-d-apiofuranosyl-(1''''→5''')-O-β-d-apiofuranosyl-(1'''→6'')]-β-d-glucopyranoside, namely sympracemoside (1), was isolated from the aerial parts of Symplocos racemosa along with 15 known flavonoids (2–16). Their structures were characterized by Q-TOF mass, optical rotation, UV, 1D and 2D-NMR spectroscopic data. Compounds 3, 9, 16 showed moderate inhibitory activities against NO production with IC₅₀ value of 88.2, 42.1 and 74.3 μM, respectively.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.