A New Sesquilignan Glucoside from Uraria sinensis

Molecules

Yingda Yang²  Zhengxi Hu²  Zengwei Luo²  Yongbo Xue²  Guangmin Yao²  Yanyan Wang¹ 

[1]First College of Clinical Medical Science of China, Three Gorges University & Yichang Central People’s Hospital, Yichang 443003, China

[2]Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

关键词: Uraria sinensis;    sesquilignan glucoside;    lignans;    flavonoids;   

DOI  :  10.3390/molecules19011178

来源: mdpi

【 摘 要 】

A new sesquilignan glucoside, urariasinoside A (1), together with eight known compounds, including two lignans, a sesquilignan, a dilignan, and four flavonoid derivatives were isolated from the aerial parts of Uraria sinensis. Their structures were determined on the basis of extensive spectroscopic analyses and comparison with literature data. Compound 1 was evaluated for in vitro cytotoxicity activity against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines.

【 授权许可】

CC BY   
© 2014 by the authors; licensee MDPI, Basel, Switzerland.