Antioxidants | |
Studies on Modulation of Gut Microbiota by Wine Polyphenols: From Isolated Cultures to Omic Approaches | |
Montserrat Dueñas3  Carolina Cueva2  Irene Muñoz-González2  Ana Jiménez-Girón2  Fernando Sánchez-Patán2  Celestino Santos-Buelga3  M. Victoria Moreno-Arribas2  Begoña Bartolomé2  Jeffrey B. Blumberg1  | |
[1]Grupo de Investigación en Polifenoles, Unidad de Nutrición y Bromatología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, Salamanca 37007, Spain | |
[2] | |
[3]Grupo de Biotecnología Enológica Aplicada, Instituto de Investigación en Ciencias de la Alimentación (CIAL), CSIC-UAM, C/Nicolás Cabrera 9, Campus de Cantoblanco, Madrid 28049, Spain | |
[4] E-Mails: | |
[5]Grupo de Investigación en Polifenoles, Unidad de Nutrición y Bromatología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, Salamanca 37007, Spain | |
[6] E-Mails: | |
关键词: wine; polyphenols; gut microbiota; probiotics; modulation; batch culture fermentation; gastrointestinal simulators; animal models; human studies; | |
DOI : 10.3390/antiox4010001 | |
来源: mdpi | |
【 摘 要 】
Moderate consumption of wine seems to produce positive health effects derived from the occurrence of bioactive polyphenols. The gut microbiota is involved in the metabolism of phenolic compounds, and these compounds and/or their metabolites may modulate gut microbiota through the stimulation of the growth of beneficial bacteria and the inhibition of pathogenic bacteria. The characterization of bacterial metabolites derived from polyphenols is essential in order to understand their effects, including microbial modulation, and therefore to associate dietary intake with particular health effects. This review aims to summarize the current information about the two-way “wine polyphenols–gut microbiota” interaction, from a perspective based on the experimental and analytical designs used. The availability of advanced methods for monitoring bacterial communities, along with the combination of
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190017850ZK.pdf | 352KB | download |