Isoleojaponin, a New Halimane Diterpene Isolated from Leonurus japonicus

Molecules

Hankui Wu¹  Sensheng Wang²  Zhiyong Xu²  Shanshan Sun²  Haijuan Liu²  Jinjin Wang²  Yan E²  Yanyan Lv²  Xuelin Dong²  Gang Li¹  Liping Zhang²  Yunfeng Shi¹ 

[1] College of Chemistry and Chemical Engineering, Anyang Normal University, Anyang 455000, Henan, China;

关键词: Leonurus japonicus;    labdane diterpenoid;    isoleojaponin;    halimane;   

DOI  :  10.3390/molecules20010839

来源: mdpi

【 摘 要 】

Leojaponin (2), a labdane diterpene, was isolated from the EtOH extract of the herb of Leonurus japonicus together with a new halimane diterpene named isoleojaponin (1). Isoleojaponin has a new diterpene skeleton with a unique cross-conjugated α,β-unsaturated ketone system, Their structures were elucidated by physical and spectroscopic analysis, and the relative configuration of the chiral C-9 carbon was determined by a computational method, and analysis of its possible biogenesis pathways.

【 授权许可】

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