Molecules | |
Emerging Structural Insights into Glycoprotein Quality Control Coupled with |
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Tadashi Satoh1  Takumi Yamaguchi1  Koichi Kato1  | |
[1] Graduate School of Pharmaceutical Sciences, Nagoya City University, 3-1 Tanabe-dori, Mizuho-ku, Nagoya 467-8603, Japan; E-Mail: | |
关键词:
calnexin/calreticulin cycle;
cargo receptor;
endoplasmic reticulum;
intracellular lectin;
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DOI : 10.3390/molecules20022475 | |
来源: mdpi | |
【 摘 要 】
In the endoplasmic reticulum (ER), the sugar chain is initially introduced onto newly synthesized proteins as a triantennary tetradecasaccharide (Glc3Man9GlcNAc2). The attached oligosaccharide chain is subjected to stepwise trimming by the actions of specific glucosidases and mannosidases. In these processes, the transiently expressed
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190016754ZK.pdf | 3220KB | download |