Electrochemical DNA Hybridization Sensors Based on Conducting Polymers

Sensors

Md. Mahbubur Rahman²  Xiao-Bo Li²  Nasrin Siraj Lopa²  Sang Jung Ahn¹ 

[1] Center for Advanced Instrumentation, Korea Research Institute of Standards and Science (KRISS), Daejeon 305-340, Korea; E-Mail:;Nanotechnology Research Center and Department of Applied Life Science, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea; E-Mails:

关键词: electrochemical DNA sensors;    conducting polymers;    immobilization techniques;    transduction mechanism;   

DOI  :  10.3390/s150203801

来源: mdpi

【 摘 要 】

Conducting polymers (CPs) are a group of polymeric materials that have attracted considerable attention because of their unique electronic, chemical, and biochemical properties. This is reflected in their use in a wide range of potential applications, including light-emitting diodes, anti-static coating, electrochromic materials, solar cells, chemical sensors, biosensors, and drug-release systems. Electrochemical DNA sensors based on CPs can be used in numerous areas related to human health. This review summarizes the recent progress made in the development and use of CP-based electrochemical DNA hybridization sensors. We discuss the distinct properties of CPs with respect to their use in the immobilization of probe DNA on electrode surfaces, and we describe the immobilization techniques used for developing DNA hybridization sensors together with the various transduction methods employed. In the concluding part of this review, we present some of the challenges faced in the use of CP-based DNA hybridization sensors, as well as a future perspective.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.