Facile Interfacial Electron Transfer of Hemoglobin Mediated by Conjugated Polymers

International Journal of Molecular Sciences

Bo Zhou³  Runguang Sun³  Xiaofang Hu¹  Lihua Wang²  Haiping Wu²  Shiping Song² 

[1] Bio-X Life Science Research Center, Shanghai Jiao Tong University, Shanghai 200030, China;Shanghai Institute of Applied Physics, Chinese Academy of Science, Shanghai 201800, China;School of Material Science and Engineering, Shanghai University, Shanghai 201800, China

关键词: Hemoglobin;    sulfonated polyaniline;    biosensors;    protein electrochemistry;    conducting polymers;   

DOI  :  10.3390/i6120303

来源: mdpi

【 摘 要 】

We herein describe a method of depositing hemoglobin (Hb) and sulfonated polyaniline (SPAN) on GC electrodes that facilitate interfacial protein electron transfer. Well-defined, reproducible, chemically reversible peaks of Hb and SPAN can be obtained in our experiments. We also observed enhanced peroxidase activity of Hb in SPAN films. These results clearly showed that SPAN worked as molecular wires and effectively exchanged electrons between Hb and electrodes.

【 授权许可】

Unknown   
© 2005 by MDPI (http://www.mdpi.org).