Oncostatin M Modulation of Lipid Storage

Biology

Carrie M. Elks¹  Jacqueline M. Stephens¹ 

[1] Adipocyte Biology Laboratory, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA 70808, USA; E-Mail:

关键词: oncostatin M;    gp130 cytokines;    adipocyte;    obesity;    adipose tissue;   

DOI  :  10.3390/biology4010151

来源: mdpi

【 摘 要 】

Oncostatin M (OSM) is a cytokine belonging to the gp130 family, whose members serve pleiotropic functions. However, several actions of OSM are unique from those of other gp130 cytokines, and these actions may have critical roles in inflammatory mechanisms influencing several metabolic and biological functions of insulin-sensitive tissues. In this review, the actions of OSM in adipose tissue and liver are discussed, with an emphasis on lipid metabolism.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.