Divinyl Sulfone Cross-Linked Cyclodextrin-Based Polymeric Materials: Synthesis and Applications as Sorbents and Encapsulating Agents

Molecules

Julia Morales-Sanfrutos¹  Francisco Javier Lopez-Jaramillo¹  Mahmoud A. A. Elremaily¹  Fernando Hernández-Mateo¹  Francisco Santoyo-Gonzalez¹ 

[1] Departamento de Química Orgánica, Facultad de Ciencias, Instituto de Biotecnología, Universidad de Granada, E1871 Granada, Spain; E-Mails:

关键词: cyclodextrins;    divinyl sulfone;    sorbents;    encapsulating agents;    phenols;    curcumin;   

DOI  :  10.3390/molecules20033565

来源: mdpi

【 摘 要 】

The aim of this study was to evaluate the crosslinking abilities of divinyl sulfone (DVS) for the preparation of novel water-insoluble cyclodextrin-based polymers (CDPs) capable of forming inclusion complexes with different guest molecules. Reaction of DVS with native α-cyclodextrin (α-CD), β-cyclodextrin (β-CD) and/or starch generates a variety of homo- and hetero-CDPs with different degrees of crosslinking as a function of the reactants’ stoichiometric ratio. The novel materials were characterized by powder X-ray diffraction, electron microscopy and for their sorption of phenol and 4-nitrophenol. They were further evaluated as sorbents with phenolic pollutants (bisphenol A and β-naphthol) and bioactive compounds (the hormone progesterone and curcumin). Data obtained from the inclusion experiments show that the degree of cross-linking has a minor influence on the yield of inclusion complex formation and highlight the important role of the CDs, supporting a sorption process based on the formation of inclusion complexes. In general, the inclusion processes are better described by a Freundlich isotherm although an important number of them can also be fitted to the Langmuir isotherm with R² ≥ 0.9, suggesting a sorption onto a monolayer of homogeneous sites.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.