Cadmium-Containing Carbonic Anhydrase CDCA1 in Marine Diatom Thalassiosira weissflogii

Marine Drugs

Vincenzo Alterio²  Emma Langella²  Giuseppina De Simone²  Simona Maria Monti¹ 

[1] Institute of Biostructures and Bioimaging—National Research Council (CNR), Via Mezzocannone 16, I-80134 Naples, Italy;

关键词: diatom;    Thalassiosira weissflogii;    carbonic anhydrase;    cadmium;    zinc;   

DOI  :  10.3390/md13041688

来源: mdpi

【 摘 要 】

The Carbon Concentration Mechanism (CCM) allows phytoplakton species to accumulate the dissolved inorganic carbon (DIC) necessary for an efficient photosynthesis even under carbon dioxide limitation. In this mechanism of primary importance for diatoms, a key role is played by carbonic anhydrase (CA) enzymes which catalyze the reversible hydration of CO₂, thus taking part in the acquisition of inorganic carbon for photosynthesis. A novel CA, named CDCA1, has been recently discovered in the marine diatom Thalassiosira weissflogii. CDCA1 is a cambialistic enzyme since it naturally uses Cd²⁺ as catalytic metal ion, but if necessary can spontaneously exchange Cd²⁺ to Zn²⁺. Here, the biochemical and structural features of CDCA1 enzyme will be presented together with its putative biotechnological applications for the detection of metal ions in seawaters.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.