Nanostructured Titanium-10 wt% 45S5 Bioglass-Ag Composite Foams for Medical Applications

Materials

Karolina Jurczyk²  Grzegorz Adamek³  Marcelina M. Kubicka¹  Jaroslaw Jakubowicz³  Mieczyslaw Jurczyk³ 

[1] Department of Genetics and Pharmaceutical Microbiology, Faculty of Pharmacy, Poznan University of Medical Sciences, Swiecickiego 4 St., 60-781 Poznan, Poland; E-Mail:;Department of Conservative Dentistry and Periodontology, Poznan University of Medical Sciences, Bukowska 70 St., 60-812 Poznan, Poland; E-Mail:;Institute of Materials Science and Engineering, Poznan University of Technology, Jana Pawla II 24 St., 61-138 Poznan, Poland; E-Mails:

关键词: biomaterials;    ceramic-metal composite;    powder metallurgy;    Staphylococcus aureus;   

DOI  :  10.3390/ma8041398

来源: mdpi

【 摘 要 】

The article presents an investigation on the effectiveness of nanostructured titanium-10 wt% 45S5 Bioglass-1 wt% Ag composite foams as a novel class of antibacterial materials for medical applications. The Ti-based composite foams were prepared by the combination of mechanical alloying and a “space-holder” sintering process. In the first step, the Ti-10 wt% 45S5 Bioglass-1 wt% Ag powder synthesized by mechanical alloying and annealing mixed with 1.0 mm diameter of saccharose crystals was finally compacted in the form of pellets. In the next step, the saccharose crystals were dissolved in water, leaving open spaces surrounded by metallic-bioceramic scaffold. The sintering of the scaffold leads to foam formation. It was found that 1:1 Ti-10 wt% 45S5 Bioglass-1 wt% Ag/sugar ratio leads to porosities of about 70% with pore diameter of about 0.3–1.1 mm. The microstructure, corrosion resistance in Ringer’s solution of the produced foams were investigated. The value of the compression strength for the Ti-10 wt% 45S5 Bioglass-1 wt% Ag foam with 70% porosity was 1.5 MPa and the Young’s modulus was 34 MPa. Silver modified Ti-10 wt% 45S5 Bioglass composites possess excellent antibacterial activities against Staphylococcus aureus. Porous Ti-10 wt% 45S5 Bioglass-1 wt% foam could be a possible candidate for medical implants applications.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.