Chitin and Chitosan as Direct Compression Excipients in Pharmaceutical Applications

Marine Drugs

Adnan A. Badwan¹  Iyad Rashid²  Mahmoud M.H. Al Omari²  Fouad H. Darras² 

[1] Research and Innovation Center (RIC), The Jordanian Pharmaceutical Manufacturing Co., P.O. Box 94, Naor 11710, Jordan;

关键词: chitin;    chitosan;    direct compression;    co-processed excipients;    solid formulation;   

DOI  :  10.3390/md13031519

来源: mdpi

【 摘 要 】

Despite the numerous uses of chitin and chitosan as new functional materials of high potential in various fields, they are still behind several directly compressible excipients already dominating pharmaceutical applications. There are, however, new attempts to exploit chitin and chitosan in co-processing techniques that provide a product with potential to act as a direct compression (DC) excipient. This review outlines the compression properties of chitin and chitosan in the context of DC pharmaceutical applications.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.