Oxidative Stress in Fungi: Its Function in Signal Transduction, Interaction with Plant Hosts, and Lignocellulose Degradation

Biomolecules

Michael Breitenbach¹  Manuela Weber²  Mark Rinnerthaler²  Thomas Karl²  Lore Breitenbach-Koller² 

[1] Department of Cell Biology, Division of Genetics, University of Salzburg, Salzburg 5020, Austria;

关键词: oxidative stress;    NADPH oxidase;    peroxiredoxin;    protein disulfide isomerase;    superoxide radical anion;    hydrogen peroxide;    hydroxyl radical;    mitochondria;    integral membrane reductases;    lignin degradation;   

DOI  :  10.3390/biom5020318

来源: mdpi

【 摘 要 】

In this review article, we want to present an overview of oxidative stress in fungal cells in relation to signal transduction, interaction of fungi with plant hosts, and lignocellulose degradation. We will discuss external oxidative stress which may occur through the interaction with other microorganisms or plant hosts as well as internally generated oxidative stress, which can for instance originate from NADPH oxidases or “leaky” mitochondria and may be modulated by the peroxiredoxin system or by protein disulfide isomerases thus contributing to redox signaling. Analyzing redox signaling in fungi with the tools of molecular genetics is presently only in its beginning. However, it is already clear that redox signaling in fungal cells often is linked to cell differentiation (like the formation of perithecia), virulence (in plant pathogens), hyphal growth and the successful passage through the stationary phase.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.